Many fundamental questions arise when anyone visit the About section of a website: what is the motivating motor that drives the team?, what do they believe in?, where they intend to go and to do with their company?,… Unfortunately, in most of the cases, this section remains a standardized flat one that let the reader dissatisfied. Indeed, it sounds often difficult to him to get a clear idea of the deep thoughts that underlie company creation.
“The only source of knowledge is experience »
In the peculiar case of INTEGRACELL, we use our 25-years expertise in oxidative stress, OXPHOS and cell metabolism. Performing research in the field of cellular metabolism, we have soon discovered that a tiny variation in one of its important pathways may lead to important modifications in whole cell behavior breaking the slight equilibrium between all that metabolic routes. An important consequence we noticed is that most of cell dysfunctions rely rather on very small variations of one or several primary or secondary metabolisms than on larger ones. Unfortunately, at the end of the nineties, measurement techniques were roughly quantifying variations, far lacking precision. Moreover, because of the need to use different techniques to measure different markers, it was not possible to measure all parameters in parallel but successively, hereby generating an unavoidable degradation of the starting material. Thus, for all that reasons, it sounds to us strongly mandatory to develop new very precise multiparametric means to be able to assess small metabolic variations in the shortest turnaround time.
Diverting the classical equipment daily used in routine clinical biology laboratories, we achieve our’s end by developing new accurate and robust methods that allow us to measure in parallel with the highest precision a large number of parameters, in a few minutes without any degradation of the starting material. As it is also possible to measure protein (or hemoglobin or DNA…) content in the same sample, we can not only quantified but also compared the different results between us. Therefore, it becomes possible to us to unambiguously define enzyme activities ratios, substrates ratios… that allow a true comparison of cell metabolism pathways function at a precise moment. Such equipment is very expensive, unaffordable for most of our collegues and necessitate a long training and expertise to be correctly used.
To give as many researchers as possible the opportunity to get such result quality, and to gain a deep insight into cell metabolism, we planned to launch a new company that will offer access to such a platform. We are now pleased to offer our services and expertise to the R&D community.
INTEGRACELL was created in 2020, drawing on its unique expertise in the field of diagnosis of cell metabolism dysfunction with a peculiar focus on oxidative stress and mitochondrial disorders.
The company owns key intellectual property related to the analytic processes that allow combined metabolism pathways analysis. It has also developed a high level know-how in integrated complex metabolic data interpretation to get a complete overview of cell metabolism and its potential perturbations.
The goal of the company is clearly to become a major key player in the field in the next future. By offering at present an already large and unique panel of accurate tests, INTEGRACELL will continuously carry on innovation to broadly and deeply explore cell metabolism.
Our future is largely driven by our vision, namely our will to offer to our customers the broadest and deepest exploration of cellular metabolism. By developing an innovating platform based on new concepts, we aimed to popularize cell substrates and enzymes measurements that are until today commonly reserved to too few specialists.
This is our foundation. Imagination without a strong knowledge and expertise will never succeed in important scientific discovery. By focusing on highest and harshest analytical performances, we become more precise and accurate that allows us to dig deeper.
By mastering the smallest details, we can deliver products that perform better, and vary less. Having the highest confidence in our results, you can let your scientific imagination go further.
For us, only refining that do exist is not enough. To go further, we want to think different to reach our needs in results fiability and reliability. This prompts us to imagine and develop a new concept of biological platform.
We do not have a customer service department. We do think we are your customer service department. You can connect directly to our team members who can propose either tests packages or tailored or customized services.
Our knowledge and expertise are at your disposal. As best as we can, we will try to adapt our services to your needs, to avoid any restriction in your imagination.
Dr Marc Conti, Pharm D, Ph.D.
President & Chief Executive Officer.
Dr Thierry Delvienne, Pharm D.
Senior Business Developer
Dr Elian Lati, Pharm D., Ph.D
Senior Scientific Advisor
Pr Sylvain Loric, Pharm D., Ph.D.
Senior Scientific Advisor
Dr. Conti leads Integracell vision to reveal metabolic insights and catalyze important breakthroughs in science and medicine. Working in Paris Pasteur Institute, he earned a Ph.D. in Biochemistry from Paris Saclay University and a Master of Science in eukaryotic Biochemistry & Molecular Biology from Paris Descartes University.
Dr. Delvienne is focused on identifying cosmetics & biopharma companies that may be interested by Integracell technical capabilities and biological areas of strategic interest.
Dr. Lati is the current owner and CEO of BioEC, a specialized company in evaluating efficacy of cosmetic and dermatological ingredients (pure or transformed ones), but also medical devices and food supplements. He earned his Ph.D. in Analytical Chemistry from Paris Saclay University
Pr. Loric counsels Integracell about scientific directions and leads its discovery & translational programs. Working in Paris Pasteur Institute, he earned a Ph.D in Molecular and Cellular Biology from Paris Descartes University and a Master of Science in Genetics from Paris Sorbonne University.